SCHEMBL28971602

SCHEMBL28971602

COC1(Cl)CC(C=O)=C(C)C=C1c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28971618 0.74 PDE4B (0.31)
SCHEMBL30705050 0.68 CYP2A6 (0.33) NPC1RAB9A
SCHEMBL28971516 0.60 HK2 (0.31)
SCHEMBL6536043 0.59
SCHEMBL6536086 0.59 USP2 (0.30)
SCHEMBL6535969 0.59
SCHEMBL27568148 0.59 ALDH1A1 (0.31)
SCHEMBL31678744 0.57 NPC1 (0.51) NPC1RAB9A
Biphenyl SCHEMBL2948084 0.56 ALDH1A1 (0.60)
Biphenyl SCHEMBL2685852 0.55 ALDH1A1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115843271-A Indole derivatives and their use for the treatment of cancer 克洛德贝纳尔-里昂第一大学 2023-03-24 CN disclosed