Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 19/20 | 0.63 |
| ▸ | DDR2 | Q16832 | 19/20 | 0.63 |
| ▸ | ABL1 | P00519 | 14/20 | 0.63 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.59 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.59 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.59 |
| ▸ | STK10 | O94804 | 1/20 | 0.59 |
| ▸ | LCK | P06239 | 1/20 | 0.59 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.59 |
| ▸ | EPHA8 | P29322 | 1/20 | 0.59 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.59 |
| ▸ | TEK | Q02763 | 1/20 | 0.59 |
| ▸ | EPHA7 | Q15375 | 1/20 | 0.59 |
| ▸ | BCR | P11274 | 2/20 | 0.54 |
| ▸ | KIT | P10721 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28971866 | 0.89 | ABL1 (0.62) | DDR1DDR2ABL1NTRK1NTRK3 | |
| SCHEMBL25339278 | 0.89 | DDR2 (0.60) | DDR1DDR2ABL1NTRK1NTRK3 | |
| SCHEMBL30211944 | 0.89 | DDR2 (0.60) | DDR1DDR2ABL1NTRK1NTRK3 | |
| SCHEMBL30211926 | 0.83 | DDR1 (0.63) | DDR1DDR2ABL1NTRK1NTRK3 | |
| SCHEMBL24070210 | 0.83 | DDR1 (0.63) | DDR1DDR2ABL1NTRK1NTRK3 | |
| SCHEMBL30211959 | 0.83 | DDR1 (0.67) | DDR1DDR2ABL1NTRK1NTRK3 | |
| SCHEMBL25338578 | 0.83 | DDR1 (0.67) | DDR1DDR2ABL1NTRK1NTRK3 | |
| SCHEMBL30211967 | 0.83 | DDR1 (0.67) | DDR1DDR2ABL1NTRK1NTRK3 | |
| SCHEMBL25337608 | 0.81 | DDR1 (0.57) | DDR1DDR2ABL1NTRK1NTRK3 | |
| SCHEMBL29864626 | 0.80 | DDR2 (0.71) | DDR1DDR2ABL1NTRK1NTRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697485-A | Benzylamine derivatives as DDR inhibitors | 奇斯药制品公司 | 2023-02-03 | — | — | CN | claimed |
| CN-115697485-A | Benzylamine derivatives as DDR inhibitors | 奇斯药制品公司 | 2023-02-03 | — | — | CN | disclosed |