Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 13/20 | 0.62 |
| ▸ | DDR2 | Q16832 | 18/20 | 0.60 |
| ▸ | DDR1 | Q08345 | 17/20 | 0.60 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.60 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.60 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.60 |
| ▸ | KIT | P10721 | 2/20 | 0.57 |
| ▸ | BCR | P11274 | 2/20 | 0.56 |
| ▸ | RET | P07949 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28971900 | 0.89 | DDR1 (0.63) | ABL1DDR2DDR1NTRK1NTRK3 | |
| SCHEMBL2976022 | 0.84 | KIT (0.68) | ABL1DDR2DDR1NTRK1NTRK3 | |
| SCHEMBL22025455 | 0.84 | DDR2 (0.65) | ABL1DDR2DDR1NTRK1NTRK3 | |
| SCHEMBL22065200 | 0.83 | DDR2 (0.60) | ABL1DDR2DDR1NTRK1NTRK3 | |
| SCHEMBL24070474 | 0.82 | DDR2 (0.66) | ABL1DDR2DDR1NTRK1NTRK3 | |
| SCHEMBL30080652 | 0.82 | KIT (0.69) | ABL1DDR2DDR1NTRK1NTRK3 | |
| SCHEMBL2965773 | 0.82 | KIT (0.69) | ABL1DDR2DDR1NTRK1NTRK3 | |
| SCHEMBL29864626 | 0.82 | DDR2 (0.71) | ABL1DDR2DDR1NTRK1NTRK3 | |
| SCHEMBL24070153 | 0.81 | ABL1 (0.70) | ABL1DDR2DDR1NTRK1NTRK3 | |
| SCHEMBL22065199 | 0.80 | DDR1 (0.63) | ABL1DDR2DDR1NTRK1NTRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697485-A | Benzylamine derivatives as DDR inhibitors | 奇斯药制品公司 | 2023-02-03 | — | — | CN | claimed |
| CN-115697485-A | Benzylamine derivatives as DDR inhibitors | 奇斯药制品公司 | 2023-02-03 | — | — | CN | disclosed |