Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.51 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4100236 | 0.72 | RAB9A (0.61) | CSNK2A1PLK3RAB9AMAPTNPC1 | |
| SCHEMBL27199981 | 0.68 | CSNK2A1 (1.00) | CSNK2A1PLK3RAB9AMAPTNPC1 | |
| SCHEMBL8625316 | 0.65 | HSD17B10 (0.42) | CSNK2A1PLK3RAB9AMAPTNPC1 | |
| SCHEMBL5157724 | 0.65 | SCN9A (0.57) | CSNK2A1PLK3RAB9AMAPTNPC1 | |
| Diphenylamine SCHEMBL9840889 | 0.65 | HSD17B10 (0.80) | RAB9AMAPTKMT2AGAAMEN1 | |
| SCHEMBL11666704 | 0.65 | RAB9A (0.59) | CSNK2A1PLK3RAB9AMAPTNPC1 | |
| SCHEMBL11578760 | 0.64 | MAPT (0.52) | CSNK2A1PLK3RAB9AMAPTKMT2A | |
| Diphenylamine SCHEMBL23722810 | 0.63 | HSD17B10 (0.57) | CSNK2A1PLK3RAB9AMAPTNPC1 | |
| Hydrochloric Acid SCHEMBL11579145 | 0.63 | MAPT (0.50) | CSNK2A1PLK3RAB9AMAPTNPC1 | |
| Hydrochloric Acid SCHEMBL11580554 | 0.63 | MAPT (0.50) | CSNK2A1PLK3RAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697980-A | Substituted aminothiazoles as DGKZETA inhibitors for immune activation | 拜耳公司 | 2023-02-03 | — | — | CN | disclosed |