Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 7/20 | 0.65 |
| ▸ | TP53 | P04637 | 6/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.65 |
| ▸ | GAA | P10253 | 4/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30218935 | 1.00 | ALDH1A1 (0.65) | ALDH1A1MAPTTP53MAPK1GAA | |
| SCHEMBL28972321 | 0.89 | SMN1; SMN2 (0.56) | ALDH1A1MAPTTP53MAPK1GAA | |
| SCHEMBL28972166 | 0.88 | NPC1 (0.60) | ALDH1A1MAPTTP53MAPK1GAA | |
| SCHEMBL30063611 | 0.87 | ALDH1A1 (0.61) | ALDH1A1MAPTTP53MAPK1GAA | |
| SCHEMBL28972318 | 0.87 | ALDH1A1 (0.61) | ALDH1A1MAPTTP53MAPK1GAA | |
| SCHEMBL28972173 | 0.86 | SMN1; SMN2 (0.64) | ALDH1A1MAPTTP53MAPK1GAA | |
| SCHEMBL30218922 | 0.86 | SMN1; SMN2 (0.64) | ALDH1A1MAPTTP53MAPK1GAA | |
| SCHEMBL27898285 | 0.83 | ALDH1A1 (0.83) | ALDH1A1MAPTTP53MAPK1GAA | |
| SCHEMBL28972251 | 0.82 | SMN1; SMN2 (0.53) | ALDH1A1MAPTTP53MAPK1GAA | |
| SCHEMBL28972142 | 0.81 | NPY5R (0.52) | ALDH1A1MAPTTP53MAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667224-A | SCL15A4 small molecule inhibitors with anti-inflammatory activity | 斯克里普斯研究学院 | 2023-01-31 | — | — | CN | disclosed |