Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10632104 | 1.00 | STK17B (0.48) | STK17BALDH1A1SMPD1TOP2AMAPT | |
| SCHEMBL10632110 | 1.00 | STK17B (0.48) | STK17BALDH1A1SMPD1TOP2AMAPT | |
| SCHEMBL10349554 | 0.93 | ALDH1A1 (0.49) | STK17BALDH1A1SMPD1TOP2AMAPT | |
| SCHEMBL10349553 | 0.93 | ALDH1A1 (0.49) | STK17BALDH1A1SMPD1TOP2AMAPT | |
| SCHEMBL4210653 | 0.87 | ALDH1A1 (0.63) | ALDH1A1TOP2AMAPTMEN1KMT2A | |
| SCHEMBL4220954 | 0.87 | ALDH1A1 (0.63) | ALDH1A1TOP2AMAPTMEN1KMT2A | |
| SCHEMBL4215918 | 0.85 | KDM4E (0.42) | ALDH1A1MEN1KMT2AAKR1C3KDM4E | |
| SCHEMBL68303 | 0.85 | KDM4E (0.42) | ALDH1A1MEN1KMT2AAKR1C3KDM4E | |
| SCHEMBL68302 | 0.85 | KDM4E (0.42) | ALDH1A1MEN1KMT2AAKR1C3KDM4E | |
| SCHEMBL2897275 | 0.84 | SMPD1 (0.47) | STK17BALDH1A1SMPD1TOP2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8357819-B2 | Method for the synthesis of (Z)-3-[2-butoxy-3′-(3-heptyl-1-methyl-ureido)-biphenyl-4-yl]-2-methoxy-acrylic acid | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2013-01-22 | — | — | US | claimed |
| EP-2146954-B1 | METHOD FOR THE SYNTHESIS OF (Z)-3-[2-BUTOXY-3'-(3-HEPTYL-1-METHYL-UREIDO)-BIPHENYL-4-YL]-2-METHOXY-ACRYLIC ACID | GALDERMA RES & DEV (FR) | 2012-10-31 | — | — | EP | claimed |
| US-20100286430-A1 | METHOD FOR THE SYNTHESIS OF (Z)-3-[2-BUTOXY-3'-(3-HEPTYL-1-METHYL-UREIDO)-BIPHENYL-4-YL]-2-METHOXY-ACRYLIC ACID | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-11-11 | — | — | US | claimed |
| US-8357819-B2 | Method for the synthesis of (Z)-3-[2-butoxy-3′-(3-heptyl-1-methyl-ureido)-biphenyl-4-yl]-2-methoxy-acrylic acid | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2013-01-22 | — | — | US | disclosed |
| US-20100286430-A1 | METHOD FOR THE SYNTHESIS OF (Z)-3-[2-BUTOXY-3'-(3-HEPTYL-1-METHYL-UREIDO)-BIPHENYL-4-YL]-2-METHOXY-ACRYLIC ACID | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286430-A1 | METHOD FOR THE SYNTHESIS OF (Z)-3-[2-BUTOXY-3'-(3-HEPTYL-1-METHYL-UREIDO)-BIPHENYL-4-YL]-2-METHOXY-ACRYLIC ACID | AZI2, UGT1A6, UGT1A3 | STK17B 3806/4885ALDH1A1 133/4885SMPD1 4826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.