Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 8/20 | 0.57 |
| ▸ | MAOB | P27338 | 4/20 | 0.57 |
| ▸ | CALML3 | P27482 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | SDHA | P31040 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28972775 | 1.00 | CYP2C19 (0.65) | CYP2C19CYP3A4CYP2C9MAOAMAOB | |
| SCHEMBL30114874 | 1.00 | CYP2C19 (0.65) | CYP2C19CYP3A4CYP2C9MAOAMAOB | |
| SCHEMBL28972839 | 0.95 | CYP2C19 (0.65) | CYP2C19CYP3A4CYP2C9MAOAMAOB | |
| SCHEMBL28972848 | 0.95 | CYP2C19 (0.65) | CYP2C19CYP3A4CYP2C9MAOAMAOB | |
| SCHEMBL28972808 | 0.94 | CYP2C19 (0.64) | CYP2C19CYP3A4CYP2C9MAOAMAOB | |
| SCHEMBL28972805 | 0.94 | CYP2C19 (0.64) | CYP2C19CYP3A4CYP2C9MAOAMAOB | |
| SCHEMBL12964525 | 0.88 | MAOA (0.55) | CYP2C19CYP3A4CYP2C9MAOAMAOB | |
| SCHEMBL28972812 | 0.88 | MAOA (0.56) | CYP2C19CYP3A4MAOAMAOBCALML3 | |
| SCHEMBL28972806 | 0.88 | MAOA (0.56) | CYP2C19CYP3A4MAOAMAOBCALML3 | |
| SCHEMBL30114844 | 0.87 | MAOA (0.63) | CYP2C19CYP3A4CYP2C9MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677679-A | Oxazolidinone compound containing biaryl hydrazone structure and preparation method and application thereof | 沈阳药科大学 | 2023-02-03 | — | — | CN | disclosed |