Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 14/20 | 0.57 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28973186 | 1.00 | AR (0.57) | ARPGRHDAC1ABCG2 | |
| SCHEMBL28973189 | 0.95 | AR (0.55) | ARPGRHDAC1 | |
| SCHEMBL28973185 | 0.95 | AR (0.55) | ARPGRHDAC1 | |
| SCHEMBL28973151 | 0.92 | AR (0.57) | ARHDAC1 | |
| SCHEMBL28973154 | 0.92 | AR (0.57) | ARHDAC1 | |
| SCHEMBL28973134 | 0.90 | AR (0.55) | ARHDAC1 | |
| SCHEMBL28973137 | 0.90 | AR (0.55) | ARHDAC1 | |
| SCHEMBL17947697 | 0.90 | AR (0.54) | ARHDAC1 | |
| SCHEMBL28984102 | 0.87 | AR (0.52) | ARHDAC1 | |
| SCHEMBL28973194 | 0.87 | AR (0.48) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115968293-A | Cereblon binding compounds, compositions thereof, and methods of use thereof for treatment | 新基公司 | 2023-04-14 | — | — | CN | disclosed |
| CN-115955979-A | Cereblan binding compounds, compositions thereof, and methods for treatment thereof | 新基公司 | 2023-04-11 | — | — | CN | disclosed |
| CN-115835866-A | Cereblon binding compounds, compositions thereof, and methods of use thereof for treatment | 新基公司 | 2023-03-21 | — | — | CN | disclosed |