Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.33 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.33 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28973118 | 1.00 | GRM2 (0.37) | GRM2SLC6A1GABRA5GABRB2SLC6A12 | |
| SCHEMBL26637297 | 1.00 | GRM2 (0.37) | GRM2SLC6A1GABRA5GABRB2SLC6A12 | |
| Trifluoroacetic Acid SCHEMBL28973146 | 0.95 | GRM2 (0.35) | GRM2SLC6A1GABRA5GABRB2SLC6A12 | |
| SCHEMBL30826013 | 0.85 | GRM2 (0.41) | GRM2HTR2AHTR2C | |
| SCHEMBL30826045 | 0.85 | GRM2 (0.41) | GRM2HTR2AHTR2C | |
| SCHEMBL7354461 | 0.83 | SLC6A1 (0.33) | SLC6A1GABRA5GABRB2SLC6A12SLC6A11 | |
| SCHEMBL29170253 | 0.81 | GRM2 (0.35) | GRM2HTR2AHTR2CHTR2B | |
| SCHEMBL30403488 | 0.81 | GRM2 (0.35) | GRM2HTR2AHTR2CHTR2B | |
| SCHEMBL29170258 | 0.81 | GRM2 (0.35) | GRM2HTR2AHTR2CHTR2B | |
| SCHEMBL28212096 | 0.81 | GRM2 (0.33) | GRM2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117715903-A | Cereblon binding compounds, compositions thereof, and methods for their use in therapy | 新基公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-117561249-A | Cereblon binding compounds, compositions thereof, and methods for their use in therapy | 细胞基因公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-115968293-A | Cereblon binding compounds, compositions thereof, and methods of use thereof for treatment | 新基公司 | 2023-04-14 | — | — | CN | disclosed |
| CN-115955979-A | Cereblan binding compounds, compositions thereof, and methods for treatment thereof | 新基公司 | 2023-04-11 | — | — | CN | disclosed |
| CN-115835866-A | Cereblon binding compounds, compositions thereof, and methods of use thereof for treatment | 新基公司 | 2023-03-21 | — | — | CN | disclosed |