Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 6/20 | 0.40 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | MARK3 | P27448 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.33 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.33 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20162629 | 0.78 | ADK (0.43) | ADKSLC29A1CHEK1DYRK3ROCK2 | |
| SCHEMBL400113 | 0.77 | ADK (0.44) | ADKSLC29A1CHEK1DYRK3ROCK2 | |
| SCHEMBL17749198 | 0.75 | ADK (0.42) | ADKSLC29A1CHEK1DYRK3ROCK2 | |
| SCHEMBL17818406 | 0.74 | ADK (0.41) | ADKSLC29A1CHEK1DYRK3ROCK2 | |
| SCHEMBL29503417 | 0.73 | ADK (0.46) | ADKSLC29A1CHEK1DYRK3ROCK2 | |
| SCHEMBL16236999 | 0.73 | ADK (0.46) | ADKSLC29A1CHEK1DYRK3ROCK2 | |
| SCHEMBL16236456 | 0.72 | ADK (0.43) | ADKSLC29A1CHEK1DYRK3ROCK2 | |
| SCHEMBL20351626 | 0.72 | ADK (0.42) | ADKSLC29A1DYRK3ROCK2PRKD3 | |
| SCHEMBL20351559 | 0.71 | ADK (0.40) | ADKSLC29A1DYRK3ROCK2PRKD3 | |
| SCHEMBL23966901 | 0.71 | ADK (0.48) | ADKSLC29A1CHEK1DYRK3ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115850268-A | Pyrrolopyrimidines as CFTR potentiators | 囊性纤维化基金会 | 2023-03-28 | — | — | CN | disclosed |