SCHEMBL28974261

SCHEMBL28974261

COC(=O)CCn1c(=O)[nH]c(=O)[nH]c1=O

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.43
APEX1 P27695 1/20 0.43
KAT2B Q92831 3/20 0.41
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 2/20 0.41
TPH1 P17752 1/20 0.38
TPH2 Q8IWU9 1/20 0.38
MAPT P10636 2/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36
KMT2A Q03164 1/20 0.36
HSD17B10 Q99714 1/20 0.36
PDE2A O00408 1/20 0.36
PDE3B Q13370 1/20 0.36
PDE3A Q14432 1/20 0.36
P2RY12 Q9H244 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24682696 0.85 APEX1 (0.61) TSHRAPEX1KAT2BALDH1A1KDM4E
SCHEMBL7344009 0.85 TSHR (0.46) TSHRAPEX1KAT2BALDH1A1KDM4E
SCHEMBL14123262 0.81 KDM4E (0.49) TSHRKAT2BALDH1A1KDM4EMAPT
SCHEMBL11655337 0.78 TSHR (0.52) TSHRAPEX1KAT2BALDH1A1KDM4E
SCHEMBL4188327 0.76 APEX1 (0.70) APEX1ALDH1A1KDM4EMAPTHTT
SCHEMBL2308197 0.75 MEN1 (0.56) TSHRALDH1A1KDM4EMAPTLMNA
SCHEMBL9850721 0.72 DAO (0.51) ALDH1A1KDM4EHSD17B10PDE2APDE3B
SCHEMBL10329440 0.72 APEX1 (0.53) TSHRAPEX1KAT2BALDH1A1KDM4E
SCHEMBL10602750 0.71 GAA (0.57) APEX1ALDH1A1KDM4EMAPTLMNA
SCHEMBL28348795 0.70 APEX1 (0.43) APEX1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115850661-A Transparent environment-friendly intrinsic flame-retardant epoxy resin material and preparation method and application thereof 华南理工大学 2023-03-28 CN claimed