Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | PPP1R15A | O75807 | 1/20 | 0.44 |
| ▸ | MELK | Q14680 | 1/20 | 0.44 |
| ▸ | PPP1R15B | Q5SWA1 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25910894 | 1.00 | L3MBTL1 (0.44) | L3MBTL1PPP1R15AMELKPPP1R15BNPSR1 | |
| SCHEMBL30369635 | 1.00 | L3MBTL1 (0.44) | L3MBTL1PPP1R15AMELKPPP1R15BNPSR1 | |
| SCHEMBL24070129 | 1.00 | L3MBTL1 (0.44) | L3MBTL1PPP1R15AMELKPPP1R15BNPSR1 | |
| SCHEMBL1691238 | 0.87 | GRIN2D (0.41) | L3MBTL1NPSR1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL1690726 | 0.87 | GRIN2D (0.41) | L3MBTL1NPSR1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL31521373 | 0.87 | GRIN2D (0.41) | L3MBTL1NPSR1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL1691240 | 0.87 | GRIN2D (0.41) | L3MBTL1NPSR1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL10110191 | 0.87 | GRIN2D (0.41) | L3MBTL1NPSR1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL30710305 | 0.87 | GRIN2D (0.41) | L3MBTL1NPSR1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL27367239 | 0.87 | GRIN2D (0.41) | L3MBTL1NPSR1SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867535-B | Substituted benzamides as modulators of TREX1 | 星座制药公司 | 2024-12-17 | — | — | CN | disclosed |
| CN-115867535-A | Substituted benzamides as modulators of TREX1 | 星座制药公司 | 2023-03-28 | — | — | CN | disclosed |