Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.69 |
| ▸ | LMNA | P02545 | 7/20 | 0.69 |
| ▸ | THRB | P10828 | 5/20 | 0.69 |
| ▸ | HTT | P42858 | 4/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 9/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3611687 | 0.92 | ALDH1A1 (0.57) | ALDH1A1LMNATHRBHTTGAA | |
| SCHEMBL13837687 | 0.86 | ALDH1A1 (0.73) | ALDH1A1LMNATHRBHTTGAA | |
| SCHEMBL3472339 | 0.81 | ALDH1A1 (1.00) | ALDH1A1LMNATHRBHTTGAA | |
| SCHEMBL3472335 | 0.81 | ALDH1A1 (1.00) | ALDH1A1LMNATHRBHTTGAA | |
| SCHEMBL12851713 | 0.81 | ALDH1A1 (0.85) | ALDH1A1LMNATHRBHTTGAA | |
| SCHEMBL8051335 | 0.80 | ALDH1A1 (0.64) | ALDH1A1LMNATHRBHTTGAA | |
| SCHEMBL8051341 | 0.80 | ALDH1A1 (0.64) | ALDH1A1LMNATHRBHTTGAA | |
| SCHEMBL2897094 | 0.79 | POLB (0.74) | ALDH1A1LMNAHTTGAAMAPT | |
| SCHEMBL3913084 | 0.77 | ALDH1A1 (0.55) | ALDH1A1LMNATHRBHTTGAA | |
| SCHEMBL3935830 | 0.77 | ALDH1A1 (0.60) | ALDH1A1LMNATHRBHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879899-B1 | THIENOPYRIDINE DERIVATIVES AS POTASSIUM CHANNEL INHIBITORS | XENTION LTD (GB) | 2010-08-04 | — | — | EP | disclosed |