Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.39 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | DTYMK | P23919 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30282831 | 1.00 | PRKCQ (0.48) | PRKCQPOLBSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL28974773 | 1.00 | PRKCQ (0.48) | PRKCQPOLBSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL29963057 | 0.86 | PRKCQ (0.43) | PRKCQPOLBALDH1A1LMNAMAPT | |
| SCHEMBL31343918 | 0.86 | SMN1; SMN2 (0.62) | PRKCQPOLBSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL28974758 | 0.83 | PRKCQ (0.46) | PRKCQSMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL10120232 | 0.83 | PRKCQ (0.46) | PRKCQSMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL31343709 | 0.83 | PRKCQ (0.46) | PRKCQSMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL17550837 | 0.83 | MAPT (0.58) | POLBALDH1A1LMNAMAPTGPR119 | |
| SCHEMBL11476913 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL31013547 | 0.77 | PRKCQ (0.52) | PRKCQPOLBSMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703765-A | Substituted triazole derivative, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2023-02-17 | — | — | CN | disclosed |