Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.49 |
| ▸ | CKS1B | P61024 | 2/20 | 0.47 |
| ▸ | SKP1 | P63208 | 2/20 | 0.47 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | DTYMK | P23919 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.44 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28974774 | 0.83 | PRKCQ (0.48) | MAPTALDH1A1LMNAPOLBGPR119 | |
| SCHEMBL30282831 | 0.83 | PRKCQ (0.48) | MAPTALDH1A1LMNAPOLBGPR119 | |
| SCHEMBL28974773 | 0.83 | PRKCQ (0.48) | MAPTALDH1A1LMNAPOLBGPR119 | |
| SCHEMBL22776812 | 0.82 | MAPT (0.49) | MAPTALDH1A1LMNAPOLBGPR119 | |
| SCHEMBL29741462 | 0.82 | CYP1A2 (0.59) | MAPTALDH1A1LMNAPOLBGPR119 | |
| SCHEMBL3336130 | 0.82 | CYP1A2 (0.59) | MAPTALDH1A1LMNAPOLBGPR119 | |
| SCHEMBL29963057 | 0.81 | PRKCQ (0.43) | MAPTALDH1A1LMNAPOLBGPR119 | |
| SCHEMBL22391780 | 0.81 | POLB (0.58) | MAPTALDH1A1LMNAPOLBGPR119 | |
| SCHEMBL10317314 | 0.81 | POLB (0.58) | MAPTALDH1A1LMNAPOLBGPR119 | |
| SCHEMBL28704879 | 0.80 | ALDH1A1 (0.50) | MAPTALDH1A1LMNAPOLBGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016030439-A1 | METHOD OF PRODUCING PALBOCICLIB AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | RATIOPHARM GMBH (DE) | 2016-03-03 | — | — | WO | disclosed |