Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOL1 | O14791 | 15/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28863435 | 0.89 | APOL1 (0.48) | APOL1 | |
| SCHEMBL30218326 | 0.81 | APOL1 (0.52) | APOL1CXCR2 | |
| SCHEMBL22118366 | 0.81 | APOL1 (0.52) | APOL1CXCR2 | |
| SCHEMBL28974880 | 0.80 | CXCR2 (0.49) | APOL1CXCR2 | |
| SCHEMBL22118430 | 0.76 | APOL1 (0.52) | APOL1CXCR2 | |
| SCHEMBL30218358 | 0.74 | APOL1 (0.40) | APOL1 | |
| SCHEMBL28974800 | 0.74 | APOL1 (0.43) | APOL1PARP1PARP2 | |
| SCHEMBL28974798 | 0.74 | APOL1 (0.40) | APOL1 | |
| SCHEMBL31312738 | 0.73 | APOL1 (0.43) | APOL1PARP1PARP2 | |
| SCHEMBL24884798 | 0.73 | PARP1 (0.41) | APOL1PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867532-A | Inhibitors of APOL1 and uses thereof | 弗特克斯药品有限公司 | 2023-03-28 | — | — | CN | disclosed |