Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 11/20 | 0.46 |
| ▸ | PDE4A | P27815 | 3/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20159457 | 0.87 | PDE4B (0.39) | PDE4BPDE4APDE4CPDE4DPDE3A | |
| SCHEMBL20159102 | 0.87 | PDE4B (0.39) | PDE4BPDE4APDE4CPDE4DPDE3A | |
| SCHEMBL20159121 | 0.87 | PDE4B (0.39) | PDE4BPDE4APDE4CPDE4DPDE3A | |
| SCHEMBL20159196 | 0.80 | PDE4B (0.43) | PDE4BPDE4APDE4CPDE4DPDE3A | |
| SCHEMBL26302297 | 0.77 | PDE3A (0.57) | PDE4BPDE4APDE4CPDE4DPDE3A | |
| SCHEMBL20159250 | 0.72 | NAMPT (0.58) | — | |
| SCHEMBL20159246 | 0.72 | NAMPT (0.58) | — | |
| SCHEMBL20138889 | 0.72 | PDE4B (0.41) | PDE4BPDE4APDE4CPDE4DPDE3A | |
| SCHEMBL20159108 | 0.71 | PDE4B (0.38) | PDE4BPDE4APDE4CPDE4DPDE3A | |
| SCHEMBL28975139 | 0.70 | PDE4A (0.65) | PDE4BPDE4APDE4CPDE4DCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867279-A | Novel oxopyridazinyl-phenyl-carbohydrazone acyldinitrile compounds and use thereof | 韩国科学技术研究院 | 2023-03-28 | — | — | CN | disclosed |