Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL303620 | 0.79 | — | — | |
| SCHEMBL1797891 | 0.77 | — | — | |
| SCHEMBL25372626 | 0.74 | MAPK10 (0.31) | — | |
| SCHEMBL28708344 | 0.73 | — | — | |
| SCHEMBL153957 | 0.72 | ATP4A (0.35) | PLA2G4ANPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL16783459 | 0.71 | CYP1A2 (0.41) | MEN1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL5638768 | 0.71 | — | — | |
| SCHEMBL18641392 | 0.70 | KMT2A (0.42) | MEN1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL1436781 | 0.70 | — | — | |
| SCHEMBL28975284 | 0.70 | KAT2B (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110950860-B | Fused tricyclic compound and application thereof in medicines | 广东东阳光药业有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-110950860-A | Fused tricyclic compound and application thereof in medicines | 广东东阳光药业有限公司 | 2020-04-03 | — | — | CN | disclosed |