Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28975801 | 1.00 | DHODH (0.81) | DHODH | |
| SCHEMBL28975757 | 0.91 | DHODH (0.76) | DHODH | |
| SCHEMBL28975753 | 0.91 | DHODH (0.76) | DHODH | |
| SCHEMBL19631388 | 0.90 | DHODH (1.00) | DHODH | |
| SCHEMBL29621431 | 0.90 | DHODH (1.00) | DHODH | |
| SCHEMBL19631436 | 0.90 | DHODH (0.85) | DHODH | |
| SCHEMBL20836131 | 0.90 | DHODH (1.00) | DHODH | |
| SCHEMBL28662893 | 0.90 | DHODH (0.75) | DHODH | |
| SCHEMBL28662894 | 0.90 | DHODH (0.75) | DHODH | |
| SCHEMBL20842825 | 0.89 | DHODH (0.82) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117769544-A | Polysubstituted thiazole derivative and application thereof in disease treatment | 上海汇伦医药股份有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-115701427-A | Polysubstituted thiazole derivatives and their use in the treatment of diseases | 上海汇伦医药股份有限公司 | 2023-02-10 | — | — | CN | disclosed |