Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28976746 | 0.86 | POLB (0.33) | OPRM1 | |
| SCHEMBL28976932 | 0.80 | KDM1A (0.39) | PARP1PARP2KDM1AMAOBSCN10A | |
| SCHEMBL28976385 | 0.79 | KDM1A (0.38) | PARP1PARP2KDM1AMAOBSCN10A | |
| SCHEMBL28976390 | 0.78 | KDM1A (0.38) | PARP1PARP2KDM1AMAOBSCN10A | |
| SCHEMBL28976619 | 0.77 | KDM1A (0.37) | PARP1PARP2KDM1AMAOBSCN10A | |
| SCHEMBL28976422 | 0.76 | KDM1A (0.36) | PARP1KDM1AMAOBSCN10AOPRM1 | |
| SCHEMBL28976512 | 0.74 | IRAK4 (0.35) | KDM1AMAOB | |
| SCHEMBL28976927 | 0.74 | PARP1 (0.33) | PARP1PARP2KDM1AMAOBSCN10A | |
| SCHEMBL28974169 | 0.72 | KDM1A (0.36) | PARP1PARP2KDM1AMAOBOPRM1 | |
| SCHEMBL28976950 | 0.71 | KDM1A (0.41) | PARP1PARP2KDM1AMAOBSCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115884810-A | Imidazopyridazines as IL-17 modulators | 詹森药业有限公司 | 2023-03-31 | — | — | CN | disclosed |