Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 11/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28976371 | 0.85 | CAMK1D (0.39) | CAMK1DIRAK4 | |
| SCHEMBL28976949 | 0.83 | CAMK1D (0.40) | CAMK1DKDM4EMAPK8PARP1PARP2 | |
| SCHEMBL28976707 | 0.77 | CAMK1D (0.39) | CAMK1DKDM4EMAPK8PARP1PARP2 | |
| SCHEMBL28976542 | 0.74 | PDE10A (0.37) | CAMK1D | |
| SCHEMBL28976326 | 0.70 | POLB (0.38) | CAMK1DPARP1PARP2 | |
| SCHEMBL28976616 | 0.70 | SCN10A (0.38) | CAMK1DKDM4EMAPK8PARP1PARP2 | |
| SCHEMBL31671010 | 0.70 | KDM4E (0.40) | NPSR1KDM4EHSD17B10L3MBTL1 | |
| SCHEMBL31670983 | 0.69 | KDM4E (0.43) | NPSR1KDM4EHSD17B10L3MBTL1 | |
| SCHEMBL28976476 | 0.69 | SCN10A (0.41) | CAMK1DKDM4EMAPK8PARP1PARP2 | |
| SCHEMBL28976931 | 0.68 | SCN10A (0.40) | CAMK1DKDM4EMAPK8PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115884810-A | Imidazopyridazines as IL-17 modulators | 詹森药业有限公司 | 2023-03-31 | — | — | CN | disclosed |