Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK1D | Q8IU85 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.33 |
| ▸ | SYK | P43405 | 2/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28976949 | 0.88 | CAMK1D (0.40) | CAMK1DPARP1PARP2GSK3AGSK3B | |
| SCHEMBL28976326 | 0.80 | POLB (0.38) | CAMK1DPARP1PARP2GSK3AGSK3B | |
| SCHEMBL28976371 | 0.78 | CAMK1D (0.39) | CAMK1DGSK3B | |
| SCHEMBL28976539 | 0.77 | CAMK1D (0.39) | CAMK1DPARP1PARP2MAPK8KDM4E | |
| SCHEMBL28976382 | 0.76 | SCN10A (0.39) | CAMK1DPARP1PARP2CYP2D6CYP2B6 | |
| SCHEMBL28976476 | 0.76 | SCN10A (0.41) | CAMK1DPARP1PARP2MAPTKDM1A | |
| SCHEMBL28976931 | 0.75 | SCN10A (0.40) | CAMK1DPARP1PARP2CYP2D6CYP2B6 | |
| SCHEMBL28976616 | 0.72 | SCN10A (0.38) | CAMK1DPARP1PARP2CYP2D6CYP2B6 | |
| SCHEMBL28976387 | 0.72 | SCN10A (0.38) | CAMK1DPARP1PARP2CYP2D6CYP2B6 | |
| SCHEMBL28976516 | 0.70 | PARP1 (0.40) | PARP1PARP2CYP2D6CYP2B6KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115884810-A | Imidazopyridazines as IL-17 modulators | 詹森药业有限公司 | 2023-03-31 | — | — | CN | disclosed |