Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 1/20 | 0.36 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.36 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | AKT2 | P31751 | 1/20 | 0.31 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29252887 | 0.87 | KDM1A (0.34) | TEAD1TEAD4TEAD2CHRNA7EPHX2 | |
| SCHEMBL30281156 | 0.84 | — | — | |
| SCHEMBL30281268 | 0.79 | SMN1; SMN2 (0.36) | TEAD1TEAD4TEAD2SMN1; SMN2HCAR2 | |
| SCHEMBL28976368 | 0.72 | KDM1A (0.32) | TEAD1TEAD4TEAD2EPHX2KDM1A | |
| SCHEMBL28976378 | 0.72 | JAK2 (0.36) | TEAD1TEAD4TEAD2CHRNA7EPHX2 | |
| SCHEMBL30281179 | 0.71 | — | — | |
| SCHEMBL26615968 | 0.69 | AKT1 (0.36) | TEAD1TEAD4TEAD2CHRNA7EPHX2 | |
| SCHEMBL2186183 | 0.68 | ALDH1A1 (0.35) | SMN1; SMN2HCAR2 | |
| SCHEMBL26615974 | 0.65 | — | — | |
| SCHEMBL30281265 | 0.65 | JAK2 (0.35) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115884810-A | Imidazopyridazines as IL-17 modulators | 詹森药业有限公司 | 2023-03-31 | — | — | CN | disclosed |