SCHEMBL2897728

SCHEMBL2897728

CCOC(C)OC(=O)C=CC(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 10/20 0.59
LMNA P02545 1/20 0.41
ALDH1A1 P00352 4/20 0.35
GAA P10253 1/20 0.35
TSHR P16473 2/20 0.35
TP53 P04637 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35
EGLN3 Q9H6Z9 1/20 0.35
GABRP O00591 2/20 0.33
GABRD O14764 2/20 0.33
GABRA1 P14867 2/20 0.33
GABRB1 P18505 2/20 0.33
GABRG2 P18507 2/20 0.33
GABRB3 P28472 2/20 0.33
GABRA5 P31644 2/20 0.33
GABRA3 P34903 2/20 0.33
GABRA2 P47869 2/20 0.33
GABRB2 P47870 2/20 0.33
GABRA4 P48169 2/20 0.33
GABRE P78334 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4880509 1.00 HCAR2 (0.59) HCAR2LMNAALDH1A1GAATSHR
SCHEMBL2897717 0.92 LMNA (0.48) HCAR2LMNATSHRATM
SCHEMBL2898080 0.92 LMNA (0.48) HCAR2LMNATSHRATM
SCHEMBL5342266 0.85 HCAR2 (0.56) HCAR2ALDH1A1GAATSHRTP53
SCHEMBL7641963 0.85 HCAR2 (0.56) HCAR2ALDH1A1GAATSHRTP53
SCHEMBL1069988 0.82 LMNA (0.42) HCAR2LMNA
SCHEMBL1069990 0.82 LMNA (0.42) HCAR2LMNA
SCHEMBL28420840 0.82 HCAR2 (0.59) HCAR2TSHRMAPTATM
SCHEMBL2890711 0.82 HCAR2 (0.59) HCAR2TSHRMAPTATM
SCHEMBL15129942 0.81 HCAR2 (0.55) HCAR2ALDH1A1GAATSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2666607-B1 TIRE BLADDER DENKA COMPANY LTD (JP) 2018-03-14 EP claimed
EP-2666607-A1 TIRE BLADDER Denki Kagaku Kogyo Kabushiki Kaisha (JP) 2013-11-27 EP claimed
US-20130295209-A1 TIRE BLADDER DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2013-11-07 US claimed
EP-0115081-B1 ELASTOMER ACRYLIC ESTER TYPE COPOLYMER DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1989-04-26 EP claimed
US-4508885-A VULCANIZED AND MOLDED YO A RUBBER COMPOUND DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1985-04-02 US claimed
EP-0115081-A2 Elastomer acrylic ester type copolymer DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1984-08-08 EP claimed
EP-2666607-B1 TIRE BLADDER DENKA COMPANY LTD (JP) 2018-03-14 EP disclosed
EP-2224279-B1 LIQUID CRYSTAL LIGHT CONTROL ELEMENT AND PROCESS FOR PRODUCING THE LIQUID CRYSTAL LIGHT CONTROL ELEMENT NIPPON SHEET GLASS CO LTD (JP) 2014-07-23 EP disclosed
EP-2666607-A1 TIRE BLADDER Denki Kagaku Kogyo Kabushiki Kaisha (JP) 2013-11-27 EP disclosed
US-20130295209-A1 TIRE BLADDER DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2013-11-07 US disclosed
US-8310626-B2 Liquid crystal light control device and method for producing the same comprising a step of emulsion polymerization of monomers of a liquid crystal resin composite NIPPON SHEET GLASS COMPANY, LIMITED (JP) 2012-11-13 US disclosed
US-20100302476-A1 LIQUID CRYSTAL LIGHT CONTROL DEVICE AND METHOD FOR PRODUCING THE SAME NIPPON SHEET GLASS COMPANY, LIMITED (JP) 2010-12-02 US disclosed
EP-2224279-A1 LIQUID CRYSTAL LIGHT CONTROL ELEMENT AND PROCESS FOR PRODUCING THE LIQUID CRYSTAL LIGHT CONTROL ELEMENT Nippon Sheet Glass Company Limited (JP) 2010-09-01 EP disclosed
EP-1097950-A1 Acrylic rubber and its composition DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2001-05-09 EP disclosed
US-5773508-A BIODEGRADABLE POLYMER OF ADDITION COPOLYMERS FOR PROTECTIVE COATINGS HITACHI CHEMICAL COMPANY, LTD. (JP) 1998-06-30 US disclosed
EP-0711813-A2 Coating varnish composition and antifouling coating composition Hitachi Chemical Co., Ltd. (JP) 1996-05-15 EP disclosed
US-4904736-A Acrylic rubber composition DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1990-02-27 US disclosed
EP-0115081-B1 ELASTOMER ACRYLIC ESTER TYPE COPOLYMER DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1989-04-26 EP disclosed
US-4508885-A VULCANIZED AND MOLDED YO A RUBBER COMPOUND DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1985-04-02 US disclosed
EP-0115081-A2 Elastomer acrylic ester type copolymer DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1984-08-08 EP disclosed