Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 12/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 11/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | FAP | Q12884 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28977841 | 0.85 | CYP3A4 (0.53) | CYP3A4CYP2D6ADORA2AADORA1FAP | |
| SCHEMBL22591959 | 0.80 | CYP3A4 (0.71) | CYP3A4CYP2D6 | |
| SCHEMBL28900522 | 0.79 | CYP3A4 (0.69) | CYP3A4CYP2D6FGFR1 | |
| SCHEMBL12150454 | 0.79 | CYP3A4 (0.64) | CYP3A4CYP2D6FAP | |
| SCHEMBL28977842 | 0.78 | CYP3A4 (0.60) | CYP3A4CYP2D6FGFR1 | |
| SCHEMBL29211968 | 0.77 | CYP3A4 (0.59) | CYP3A4CYP2D6ADORA2AADORA1FGFR1 | |
| Tenofovir Anhydrous SCHEMBL2040329 | 0.77 | CYP3A4 (1.00) | CYP3A4CYP2D6FAPFGFR1SLC22A6 | |
| Tenofovir Anhydrous SCHEMBL497725 | 0.77 | CYP3A4 (1.00) | CYP3A4CYP2D6FAPFGFR1SLC22A6 | |
| Tenofovir Anhydrous SCHEMBL39724 | 0.77 | CYP3A4 (1.00) | CYP3A4CYP2D6FAPFGFR1SLC22A6 | |
| Tenofovir Anhydrous SCHEMBL18894359 | 0.77 | CYP3A4 (1.00) | CYP3A4CYP2D6FAPFGFR1SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116355017-A | Novel nucleoside reverse transcriptase inhibitors for antiviral use | 深圳市塔吉瑞生物医药有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-109485676-B | Novel nucleoside reverse transcriptase inhibitors for antiviral use | 深圳市塔吉瑞生物医药有限公司 | 2022-07-15 | — | — | CN | disclosed |