Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31586070 | 0.91 | NR3C1 (0.43) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL25581203 | 0.91 | NR3C1 (0.43) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL30822383 | 0.89 | FFAR4 (0.44) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL29227486 | 0.89 | FFAR4 (0.44) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL31586917 | 0.89 | NR3C1 (0.42) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL25221532 | 0.89 | NR3C1 (0.42) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL31255497 | 0.89 | PRSS1 (0.44) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL29384475 | 0.89 | NR3C1 (0.42) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL31586097 | 0.88 | AKR1C3 (0.41) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL31586935 | 0.88 | NR3C1 (0.41) | NR3C1PGRSLC6A4KCNH2PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115710274-A | IRAK4 degradation agent, preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2023-02-24 | — | — | CN | disclosed |