Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28978082 | 1.00 | ATM (0.40) | ATMALDH1A1GAAGFERAAK1 | |
| SCHEMBL29856186 | 1.00 | ATM (0.40) | ATMALDH1A1GAAGFERAAK1 | |
| SCHEMBL28310907 | 1.00 | ATM (0.40) | ATMALDH1A1GAAGFERAAK1 | |
| SCHEMBL20529471 | 0.93 | ATM (0.42) | ATMALDH1A1GAAGFERAAK1 | |
| SCHEMBL20529408 | 0.93 | ATM (0.42) | ATMALDH1A1GAAGFERAAK1 | |
| SCHEMBL29467732 | 0.93 | ATM (0.42) | ATMALDH1A1GAAGFERAAK1 | |
| SCHEMBL20529409 | 0.93 | ATM (0.42) | ATMALDH1A1GAAGFERAAK1 | |
| SCHEMBL29467655 | 0.93 | ATM (0.42) | ATMALDH1A1GAAGFERAAK1 | |
| SCHEMBL24117993 | 0.92 | ALDH1A1 (0.43) | ATMALDH1A1GAAGFERAAK1 | |
| SCHEMBL28310908 | 0.90 | ATM (0.38) | ATMALDH1A1GAAGFERAAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143678-A | Conjugate linker, cell-binding molecule-drug conjugate containing the same, and preparation and application thereof | 杭州多禧生物科技有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-110099682-B | Coupled connector, cell binding molecule-drug conjugate containing same, and preparation and application thereof | 杭州多禧生物科技有限公司 | 2023-03-31 | — | — | CN | disclosed |