Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8356708 | 0.87 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2HPGDEGFR | |
| SCHEMBL27396917 | 0.86 | SMN1; SMN2 (0.71) | NPC1RAB9ASMN1; SMN2HPGDEGFR | |
| SCHEMBL10604837 | 0.84 | EGFR (0.65) | NPC1RAB9ASMN1; SMN2HPGDEGFR | |
| SCHEMBL4295650 | 0.84 | FOLH1 (0.62) | NPC1RAB9ASMN1; SMN2HPGDEGFR | |
| SCHEMBL11875558 | 0.84 | SMN1; SMN2 (0.57) | NPC1RAB9ASMN1; SMN2HPGDEGFR | |
| SCHEMBL6895376 | 0.84 | PARP1 (0.57) | NPC1RAB9ASMN1; SMN2HPGDEGFR | |
| SCHEMBL4161097 | 0.83 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2HPGDEGFR | |
| SCHEMBL5468617 | 0.83 | MRGPRX4 (0.57) | NPC1RAB9ASMN1; SMN2HPGDEGFR | |
| SCHEMBL1437989 | 0.83 | FFAR4 (0.58) | NPC1RAB9ASMN1; SMN2HPGDEGFR | |
| SCHEMBL2009073 | 0.83 | CREBBP (0.66) | NPC1RAB9ASMN1; SMN2HPGDMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115873909-B | Preparation method of arformoterol chiral intermediate | 天津法莫西生物医药科技有限公司 | 2023-08-11 | — | — | CN | claimed |
| CN-115873909-A | Preparation method of arformoterol chiral intermediate | 天津法莫西生物医药科技有限公司 | 2023-03-31 | — | — | CN | claimed |
| CN-115873909-B | Preparation method of arformoterol chiral intermediate | 天津法莫西生物医药科技有限公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-115873909-A | Preparation method of arformoterol chiral intermediate | 天津法莫西生物医药科技有限公司 | 2023-03-31 | — | — | CN | disclosed |