Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL510148 | 0.96 | CHRM2 (0.36) | CHRM2CHRM1CHRM5CHRM3OPRD1 | |
| SCHEMBL27711825 | 0.95 | CHRM2 (0.36) | CHRM2CHRM1CHRM5CHRM3OPRD1 | |
| Alcohol SCHEMBL9343023 | 0.89 | SMN1; SMN2 (0.38) | CHRM5CHRM3OPRD1SIGMAR1SMN1; SMN2 | |
| Sulfuric Acid SCHEMBL27952192 | 0.87 | CHRM2 (0.39) | CHRM2CHRM1CHRM5CHRM3OPRD1 | |
| SCHEMBL6482532 | 0.86 | SIGMAR1 (0.36) | CHRM2CHRM1CHRM5CHRM3OPRD1 | |
| SCHEMBL23011994 | 0.83 | CHRM2 (0.35) | CHRM2CHRM1CHRM5CHRM3LMNA | |
| Propane SCHEMBL3983224 | 0.82 | SMN1; SMN2 (0.39) | CHRM5CHRM3OPRD1SIGMAR1SMN1; SMN2 | |
| SCHEMBL11027147 | 0.81 | SMN1; SMN2 (0.33) | CHRM2CHRM1CHRM5CHRM3OPRD1 | |
| SCHEMBL28511449 | 0.81 | CHRM5 (0.35) | CHRM2CHRM1CHRM5CHRM3OPRD1 | |
| SCHEMBL8373239 | 0.80 | SMN1; SMN2 (0.38) | CHRM2CHRM1CHRM5CHRM3OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112147113-B | Application of coumarin derivative in quantitative detection of sulfur dioxide | 西南交通大学 | 2023-04-07 | — | — | CN | claimed |