Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.67 |
| ▸ | AXL | P30530 | 1/20 | 0.67 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.67 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.67 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.67 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.60 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6196239 | 0.80 | CYP19A1 (1.00) | CYP19A1AXLPBRM1MKNK1MKNK2 | |
| SCHEMBL28232733 | 0.79 | KDM4E (0.59) | CYP19A1RAB9AKDM4EHPGDNPC1 | |
| SCHEMBL27820489 | 0.79 | KDM4E (0.53) | CYP19A1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL266591 | 0.79 | CYP2E1 (1.00) | CYP19A1AXLPBRM1MKNK1MKNK2 | |
| SCHEMBL9829144 | 0.79 | CYP19A1 (0.67) | CYP19A1AXLPBRM1MKNK1MKNK2 | |
| SCHEMBL14359963 | 0.79 | CYP19A1 (0.67) | CYP19A1AXLPBRM1MKNK1MKNK2 | |
| SCHEMBL1722906 | 0.79 | CYP19A1 (0.67) | CYP19A1AXLPBRM1MKNK1MKNK2 | |
| SCHEMBL12402375 | 0.79 | CYP19A1 (0.67) | CYP19A1AXLPBRM1MKNK1MKNK2 | |
| SCHEMBL5377137 | 0.78 | CYP19A1 (0.61) | CYP19A1AXLPBRM1MKNK1MKNK2 | |
| SCHEMBL21408714 | 0.78 | CYP19A1 (0.40) | CYP19A1AXLPBRM1MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9756858-B2 | Insecticides | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-12 | — | — | US | disclosed |
| US-9756858-B2 | Insecticides | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-12 | — | — | US | disclosed |
| US-9756858-B2 | Insecticides | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-12 | — | — | US | disclosed |
| CN-104540821-B | Process for preparing certain 2- (pyridin-3-yl) thiazoles | 美国陶氏益农公司 | 2017-07-18 | — | — | CN | disclosed |
| EP-2614826-B1 | Process for preparation of thiazole derivatives | DOW AGROSCIENCES LLC (US) | 2017-03-01 | — | — | EP | disclosed |
| EP-2614826-B1 | Process for preparation of thiazole derivatives | DOW AGROSCIENCES LLC (US) | 2017-03-01 | — | — | EP | disclosed |
| US-9357780-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2016-06-07 | — | — | US | disclosed |
| US-9357780-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2016-06-07 | — | — | US | disclosed |
| US-9357780-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2016-06-07 | — | — | US | disclosed |
| EP-2614825-B1 | Process for the preparation of thiazole derivatives | DOW AGROSCIENCES LLC (US) | 2016-03-16 | — | — | EP | disclosed |
| WO-2012168361-A1 | NOVEL INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-12-13 | — | — | WO | disclosed |
| EP-2532661-A1 | Novel insecticides | Syngenta Participations AG (CH) | 2012-12-12 | — | — | EP | disclosed |
| EP-2532661-A1 | Novel insecticides | Syngenta Participations AG (CH) | 2012-12-12 | — | — | EP | disclosed |
| CN-102458403-A | insecticidal composition | DOW AGROSCIENCES LLC | 2012-05-16 | — | — | CN | disclosed |
| EP-2427191-A1 | PESTICIDAL COMPOSITIONS | Dow AgroSciences LLC (US) | 2012-03-14 | — | — | EP | disclosed |
| US-20100292253-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2010-11-18 | — | — | US | disclosed |
| US-20100292253-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2010-11-18 | — | — | US | disclosed |
| US-20100292253-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2010-11-18 | — | — | US | disclosed |
| WO-2010129497-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2010-11-11 | — | — | WO | disclosed |
| WO-2010129497-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2010-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292253-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PRDX6 | CYP19A1 234/4885AXL 4147/4885PBRM1 4590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.