Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.34 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.30 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3521419 | 0.83 | CHRNB2 (0.36) | CA2CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL3507166 | 0.83 | KDM4E (0.35) | CA2CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL27921094 | 0.76 | DPP4 (0.41) | CA2CHKACHRNB2CHRNA3CHRNA4 | |
| SCHEMBL28330960 | 0.76 | DPP4 (0.41) | CA2CHKACHRNB2CHRNA3CHRNA4 | |
| SCHEMBL27754028 | 0.75 | GAA (0.37) | TSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28060473 | 0.74 | DPP4 (0.40) | CA2CHKACHRNB2CHRNA3CHRNA4 | |
| SCHEMBL28312822 | 0.74 | PARP1 (0.46) | SMN1; SMN2 | |
| SCHEMBL28979452 | 0.71 | HTR2C (0.32) | CA2CHKACHRNB2CHRNA3CHRNA4 | |
| SCHEMBL6832473 | 0.69 | — | — | |
| SCHEMBL28454116 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916776-A | Collagen 1 translation inhibitors and methods of use thereof | 艾尼莫生物科技公司 | 2023-04-04 | — | — | CN | claimed |
| CN-115916776-A | Collagen 1 translation inhibitors and methods of use thereof | 艾尼莫生物科技公司 | 2023-04-04 | — | — | CN | disclosed |