Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PGD | P52209 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28530549 | 0.83 | LMNA (0.41) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28530548 | 0.83 | LMNA (0.41) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL29728569 | 0.83 | LMNA (0.44) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL3262366 | 0.83 | LMNA (0.44) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL29728537 | 0.76 | LMNA (0.40) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28979601 | 0.72 | LMNA (0.34) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL8266675 | 0.72 | — | — | |
| SCHEMBL15374300 | 0.72 | — | — | |
| SCHEMBL3355488 | 0.72 | — | — | |
| SCHEMBL29728555 | 0.70 | LMNA (0.39) | LMNACHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563033-B | Aliphatic prolinamide derivatives | 奥瑞恩眼科有限责任公司 | 2023-04-04 | — | — | CN | disclosed |