Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28849635 | 0.98 | EPHX2 (0.45) | EPHX2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8386558 | 0.84 | EPHX2 (0.47) | EPHX2SERPINE1EPHX1TRPV1SLC6A2 | |
| SCHEMBL15504635 | 0.81 | MAPT (0.57) | EPHX2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL594774 | 0.79 | MAPT (0.43) | EPHX2HDAC3HDAC1HDAC2SERPINE1 | |
| SCHEMBL28904603 | 0.78 | CA1 (0.48) | POLBKMT2AMEN1NPC1TSHR | |
| SCHEMBL28486440 | 0.78 | SERPINE1 (0.47) | EPHX2HDAC8SERPINE1EPHX1KMT2A | |
| Hydrochloric Acid SCHEMBL5797916 | 0.77 | GRIN2B (0.47) | TRPV1SLC6A2SLC6A4KMT2AMEN1 | |
| SCHEMBL3597003 | 0.77 | SMN1; SMN2 (0.46) | EPHX2HDAC6 | |
| SCHEMBL12638458 | 0.76 | SERPINE1 (0.46) | EPHX2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13871456 | 0.76 | EPHX2 (0.46) | EPHX2HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894326-B | 2, 3-Hydrogen substituted aminoindole derivative, preparation method and application thereof | 佛山大学 | 2025-02-11 | — | — | CN | disclosed |
| CN-115894326-A | 2,3-hydrogen substituted aminoindole derivative, preparation method and application thereof | 佛山科学技术学院 | 2023-04-04 | — | — | CN | disclosed |