Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 2/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.46 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1875890 | 0.86 | SERPINE1 (0.49) | MAPTPOLBEPHX2HDAC3HDAC4 | |
| SCHEMBL13871456 | 0.84 | EPHX2 (0.46) | MAPTPOLBALDH1A1EPHX2HDAC3 | |
| SCHEMBL5535914 | 0.84 | GPBAR1 (0.46) | MAPTPOLBALDH1A1EPHX2HDAC3 | |
| SCHEMBL28865681 | 0.83 | EPHX2 (0.42) | MAPTSMN1; SMN2POLBALDH1A1EPHX2 | |
| SCHEMBL23084362 | 0.82 | MAPT (0.47) | MAPTALDH1A1HTTEPHX2LMNA | |
| SCHEMBL21649311 | 0.81 | POLB (0.48) | POLBEPHX2LMNAHDAC3HDAC4 | |
| SCHEMBL14518800 | 0.81 | MLYCD (0.59) | ALDH1A1HTTEPHX2LMNAHDAC3 | |
| SCHEMBL28980342 | 0.81 | EPHX2 (0.46) | POLBEPHX2HDAC3HDAC4HDAC1 | |
| SCHEMBL22312030 | 0.80 | POLB (0.43) | POLBEPHX2LMNAHDAC3HDAC4 | |
| SCHEMBL7665673 | 0.80 | PAX8 (0.45) | HTTEPHX2LMNARXRANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11160280-B2 | Pesticial compounds | BASF SE (DE) | 2021-11-02 | — | — | US | disclosed |
| US-20200029566-A1 | Pesticial Compounds | BASF SE (DE) | 2020-01-30 | — | — | US | disclosed |
| WO-2014039714-A2 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC. (US) | 2014-03-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11160280-B2 | Pesticial compounds | PNMT, DDT, NIT2 | MAPT 108/4885SMN1; SMN2 679/4885POLB 2894/4885 |
| US-20200029566-A1 | Pesticial Compounds | PNMT, DDT, NIT2 | MAPT 108/4885SMN1; SMN2 679/4885POLB 2894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.