Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28980328 | 0.80 | KDM4E (0.31) | — | |
| SCHEMBL28980331 | 0.80 | KDM4E (0.31) | — | |
| SCHEMBL567560 | 0.75 | — | — | |
| SCHEMBL4837235 | 0.74 | AAK1 (0.31) | — | |
| SCHEMBL4837241 | 0.74 | AAK1 (0.31) | — | |
| SCHEMBL28980349 | 0.73 | — | — | |
| SCHEMBL22536843 | 0.73 | — | — | |
| SCHEMBL7718969 | 0.71 | L3MBTL1 (0.30) | — | |
| SCHEMBL13405163 | 0.71 | — | — | |
| SCHEMBL7719949 | 0.70 | EPHX2 (0.33) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115925721-A | Pyrimidone tricyclic derivative, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2023-04-07 | — | — | CN | disclosed |