Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | NOS3 | P29474 | 3/20 | 0.32 |
| ▸ | NOS2 | P35228 | 3/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34472956 | 0.97 | PDE3B (0.39) | PDE3BPDE3ANOS3NOS2NOS1 | |
| SCHEMBL1131513 | 0.97 | PDE3B (0.39) | PDE3BPDE3ANOS3NOS2NOS1 | |
| SCHEMBL28865690 | 0.85 | PDE3B (0.34) | PDE3BPDE3ANOS3NOS2NOS1 | |
| SCHEMBL18641591 | 0.83 | PDE3B (0.39) | PDE3BPDE3ANOS2 | |
| SCHEMBL17370232 | 0.83 | PDE3B (0.33) | PDE3BPDE3A | |
| SCHEMBL23920165 | 0.83 | PDE3B (0.33) | PDE3BPDE3ANOS3NOS2NOS1 | |
| SCHEMBL29364887 | 0.83 | PDE3B (0.39) | PDE3BPDE3ANOS2 | |
| SCHEMBL17370233 | 0.83 | PDE3B (0.33) | PDE3BPDE3ANOS3NOS2 | |
| SCHEMBL7497070 | 0.83 | PDE3B (0.33) | PDE3BPDE3ANOS3NOS2NOS1 | |
| SCHEMBL4686333 | 0.83 | PDE3B (0.33) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107567443-B | Biaryl derivatives as GPR120 agonists | 株式会社LG化学 | 2023-04-28 | — | — | CN | disclosed |
| CN-115925679-A | Biaryl derivatives as GPR120 agonists | 株式会社LG化学 | 2023-04-07 | — | — | CN | disclosed |