Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1131513 | 0.86 | PDE3B (0.39) | PDE3BPDE3A | |
| SCHEMBL1532108 | 0.86 | — | — | |
| SCHEMBL34472956 | 0.86 | PDE3B (0.39) | PDE3BPDE3A | |
| Ammonia Solution, Strong SCHEMBL28980458 | 0.83 | PDE3B (0.38) | PDE3BPDE3A | |
| SCHEMBL28865690 | 0.76 | PDE3B (0.34) | PDE3BPDE3A | |
| SCHEMBL23920165 | 0.74 | PDE3B (0.33) | PDE3BPDE3A | |
| SCHEMBL18641591 | 0.74 | PDE3B (0.39) | PDE3BPDE3A | |
| SCHEMBL17370233 | 0.74 | PDE3B (0.33) | PDE3BPDE3A | |
| SCHEMBL24135655 | 0.74 | — | — | |
| SCHEMBL29364887 | 0.74 | PDE3B (0.39) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9371521-B2 | Substituted pyrazinedithiol reducing agents | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2016-06-21 | — | — | US | disclosed |
| US-20150376591-A1 | SUBSTITUTED PYRAZINE DITHIOL REDUCING AGENTS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2015-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150376591-A1 | SUBSTITUTED PYRAZINE DITHIOL REDUCING AGENTS | SPR, TST, SQOR | PDE3B 3614/4885PDE3A 2883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.