Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 12/20 | 0.64 |
| ▸ | FGFR1 | P11362 | 7/20 | 0.64 |
| ▸ | HCK | P08631 | 1/20 | 0.64 |
| ▸ | EGFR | P00533 | 2/20 | 0.64 |
| ▸ | MAP3K7 | O43318 | 9/20 | 0.63 |
| ▸ | MAP2K1 | Q02750 | 6/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.63 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.57 |
| ▸ | FLT3 | P36888 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30905168 | 1.00 | SRC (0.64) | SRCFGFR1HCKEGFRMAP3K7 | |
| SCHEMBL31684790 | 0.90 | MAP3K7 (0.70) | SRCFGFR1HCKMAP3K7MAP2K1 | |
| SCHEMBL28980988 | 0.90 | MAP3K7 (0.70) | SRCFGFR1HCKMAP3K7MAP2K1 | |
| SCHEMBL28981021 | 0.90 | SRC (0.67) | SRCFGFR1HCKMAP3K7MAP2K1 | |
| SCHEMBL31684769 | 0.90 | SRC (0.78) | SRCFGFR1HCKEGFRMAP3K7 | |
| SCHEMBL28980989 | 0.90 | SRC (0.78) | SRCFGFR1HCKEGFRMAP3K7 | |
| SCHEMBL22807459 | 0.89 | SRC (0.80) | SRCFGFR1HCKEGFRMAP3K7 | |
| SCHEMBL28980966 | 0.87 | MAP3K7 (0.71) | SRCFGFR1HCKMAP3K7MAP2K1 | |
| SCHEMBL17002254 | 0.85 | EGFR (0.85) | SRCEGFRPTK2 | |
| SCHEMBL22807446 | 0.83 | SRC (0.90) | SRCFGFR1HCKMAP3K7MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894381-A | 2,4,5-trisubstituted pyrimidine compound and preparation method and application thereof | 温州医科大学 | 2023-04-04 | — | — | CN | claimed |
| CN-115894381-A | 2,4,5-trisubstituted pyrimidine compound and preparation method and application thereof | 温州医科大学 | 2023-04-04 | — | — | CN | disclosed |