Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 13/20 | 0.78 |
| ▸ | FGFR1 | P11362 | 11/20 | 0.78 |
| ▸ | MAP3K7 | O43318 | 8/20 | 0.78 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.78 |
| ▸ | EGFR | P00533 | 2/20 | 0.66 |
| ▸ | MAPK3 | P27361 | 3/20 | 0.65 |
| ▸ | HCK | P08631 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28980989 | 1.00 | SRC (0.78) | SRCFGFR1MAP3K7MAP2K1MAPK1 | |
| SCHEMBL30905168 | 0.90 | SRC (0.64) | SRCFGFR1MAP3K7MAP2K1MAPK1 | |
| SCHEMBL28980975 | 0.90 | SRC (0.64) | SRCFGFR1MAP3K7MAP2K1MAPK1 | |
| SCHEMBL28980984 | 0.89 | SRC (0.82) | SRCFGFR1MAP3K7MAP2K1MAPK1 | |
| SCHEMBL31684786 | 0.88 | SRC (1.00) | SRCFGFR1MAP3K7MAP2K1MAPK1 | |
| SCHEMBL22807490 | 0.88 | SRC (0.83) | SRCFGFR1MAP3K7MAP2K1MAPK1 | |
| SCHEMBL22828520 | 0.88 | SRC (1.00) | SRCFGFR1MAP3K7MAP2K1MAPK1 | |
| SCHEMBL17002254 | 0.87 | EGFR (0.85) | SRCEGFR | |
| SCHEMBL22807493 | 0.87 | SRC (0.82) | SRCFGFR1MAP3K7MAP2K1MAPK1 | |
| SCHEMBL22807377 | 0.87 | SRC (0.82) | SRCFGFR1MAP3K7MAP2K1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4617261-A1 | 2,4,5-TRISUBSTITUTED PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | Wenzhou Medical University (CN) | 2025-09-17 | — | — | EP | claimed |