Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL25173595 | 0.89 | PTK6 (0.33) | PTK6BRD4BRDT | |
| SCHEMBL28982236 | 0.84 | KDM4E (0.36) | PTK6KDM4EGAASMN1; SMN2BRD4 | |
| SCHEMBL22124281 | 0.84 | PTK6 (0.42) | PTK6LCK | |
| SCHEMBL22124283 | 0.84 | PTK6 (0.42) | PTK6LCK | |
| SCHEMBL22123871 | 0.84 | PTK6 (0.40) | PTK6KDM4EGAASMN1; SMN2LCK | |
| SCHEMBL30402648 | 0.84 | PTK6 (0.47) | PTK6KDM4EGAASMN1; SMN2BRD4 | |
| SCHEMBL22124741 | 0.83 | PTK6 (0.40) | PTK6LCK | |
| SCHEMBL24112493 | 0.82 | PTK6 (0.41) | PTK6LCK | |
| SCHEMBL25452721 | 0.81 | PTK6 (0.40) | PTK6LCK | |
| SCHEMBL22124671 | 0.81 | PTK6 (0.38) | PTK6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161931-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-04-12 | — | — | EP | disclosed |
| CN-115916784-A | Novel imidazopyrazine derivatives | 豪夫迈·罗氏有限公司 | 2023-04-04 | — | — | CN | disclosed |