Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 5/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.52 |
| ▸ | CYP2E1 | P05181 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | G6PD | P11413 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | USP8 | P40818 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2893816 | 0.85 | NPC1 (0.65) | CYP2A6CYP2C19CYP2E1CYP2C9CYP2B6 | |
| SCHEMBL6172906 | 0.81 | CYP2A6 (0.56) | CYP2A6CYP2C19CYP2E1CYP2C9CYP2B6 | |
| SCHEMBL2899672 | 0.80 | CYP2A6 (0.49) | CYP2A6CYP2C19CYP2E1CYP2C9CYP2B6 | |
| SCHEMBL999177 | 0.75 | CYP2A6 (0.62) | CYP2A6CYP2C19CYP2E1CYP2C9CYP2B6 | |
| SCHEMBL5792405 | 0.75 | CYP2A6 (0.49) | CYP2A6CYP2C19CYP2E1CYP2C9CYP2B6 | |
| SCHEMBL5792876 | 0.74 | CYP2A6 (0.48) | CYP2A6CYP2C19CYP2E1CYP2C9CYP2B6 | |
| SCHEMBL2732909 | 0.73 | CYP2A6 (0.50) | CYP2A6CYP2C19CYP2E1CYP2C9CYP2B6 | |
| SCHEMBL15747849 | 0.72 | CYP2A6 (0.59) | CYP2A6CYP2C19CYP2E1CYP2C9CYP2B6 | |
| SCHEMBL27381147 | 0.72 | GRIN2D (0.38) | NPC1RAB9ANLRP3MAPTKDM4E | |
| SCHEMBL27584243 | 0.71 | CYP2A6 (0.55) | CYP2A6CYP2C19CYP2E1CYP2C9CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286211-A1 | OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS | RANBAXY LABORATORIES LIMITED (IN) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286211-A1 | OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS | OXA1L, PDK4, MLYCD | CYP2A6 702/4885CYP2C19 273/4885CYP2E1 799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.