SCHEMBL28983476

SCHEMBL28983476

CCCCC1CCc2c(c3cccc(C(=O)O)c3n2Cc2cccc(C#N)c2)C1

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ FABP4 P15090 18/20 0.48
▸ FABP3 P05413 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28983453 0.97 FABP4 (0.48) FABP4FABP3
SCHEMBL30317500 0.97 FABP4 (0.48) FABP4FABP3
SCHEMBL28983433 0.95 FABP4 (0.50) FABP4FABP3
SCHEMBL30317270 0.95 FABP4 (0.50) FABP4FABP3
SCHEMBL30317471 0.92 FABP4 (0.46) FABP4FABP3
SCHEMBL30398457 0.91 FABP4 (0.52) FABP4FABP3
SCHEMBL28983421 0.91 FABP4 (0.48) FABP4FABP3
SCHEMBL30317417 0.91 FABP4 (0.48) FABP4FABP3
SCHEMBL24155513 0.90 FABP4 (0.52) FABP4FABP3
SCHEMBL30317285 0.90 FABP4 (0.47) FABP4FABP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116761598-A Antiviral use of FABP4 modulating compounds 新月生物科学 2023-09-15 — — CN claimed
EP-4175647-A1 ANTIVIRAL USE OF FABP4 MODULATING COMPOUNDS Crescenta Biosciences (US) 2023-05-10 — — EP claimed
EP-4171736-A1 NOVEL CELL METABOLISM MODULATING COMPOUNDS AND USES THEREOF Crescenta Biosciences (US) 2023-05-03 — — EP claimed
CN-115803085-A Novel cell metabolism regulating compounds and uses 新月生物科学 2023-03-14 — — CN claimed
CN-116761598-A Antiviral use of FABP4 modulating compounds 新月生物科学 2023-09-15 — — CN disclosed
EP-4175647-A1 ANTIVIRAL USE OF FABP4 MODULATING COMPOUNDS Crescenta Biosciences (US) 2023-05-10 — — EP disclosed
EP-4171736-A1 NOVEL CELL METABOLISM MODULATING COMPOUNDS AND USES THEREOF Crescenta Biosciences (US) 2023-05-03 — — EP disclosed
CN-115803085-A Novel cell metabolism regulating compounds and uses 新月生物科学 2023-03-14 — — CN disclosed
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