Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.46 |
| ▸ | PDE4A | P27815 | 2/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28983485 | 0.90 | GPR119 (0.50) | KDM1APDE4BPDE4DPDE4APDE4C | |
| SCHEMBL1446669 | 0.88 | KDM1A (0.48) | KDM1APDE4BPDE4DPDE4APDE4C | |
| SCHEMBL28983500 | 0.87 | GPR119 (0.46) | KDM1APDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7364955 | 0.86 | PDE4B (0.54) | KDM1APDE4BPDE4DPDE4APDE4C | |
| SCHEMBL15363254 | 0.85 | KDM1A (0.48) | KDM1APDE4BPDE4DPDE4APDE4C | |
| SCHEMBL28983510 | 0.83 | GPR119 (0.45) | KDM1APDE4BPDE4DPDE4APDE4C | |
| SCHEMBL25318077 | 0.83 | PDE4B (0.47) | KDM1APDE4BPDE4DPDE4APDE4C | |
| SCHEMBL30986535 | 0.83 | PDE4B (0.47) | KDM1APDE4BPDE4DPDE4APDE4C | |
| SCHEMBL5971118 | 0.81 | PDE4B (0.53) | KDM1APDE4BPDE4DPDE4APDE4C | |
| SCHEMBL28779854 | 0.81 | IKBKB (0.47) | PDE4BIKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115803326-B | EGFR inhibitor, preparation method thereof and application thereof in pharmacy | 上海和誉生物医药科技有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-115803326-A | EGFR inhibitor, preparation method and pharmaceutical application thereof | 上海和誉生物医药科技有限公司 | 2023-03-14 | — | — | CN | disclosed |
| WO-2022105908-A1 | EGFR INHIBITOR, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF | 上海和誉生物医药科技有限公司 | 2022-05-27 | — | — | WO | disclosed |