Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.45 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11359782 | 0.82 | TSHR (0.56) | TSHRKMT2AGAAMAPTPKM | |
| SCHEMBL23732187 | 0.79 | TSHR (0.47) | TSHRKMT2AGAAMAPTALDH1A1 | |
| SCHEMBL14830469 | 0.79 | KDM4E (0.47) | TSHRKMT2AGAAMAPTALDH1A1 | |
| SCHEMBL15568745 | 0.78 | KMT2A (0.34) | KMT2AGAAMAPTPKMALDH1A1 | |
| SCHEMBL1220842 | 0.78 | ALDH1A1 (0.52) | TSHRKMT2AGAAMAPTALDH1A1 | |
| SCHEMBL27077665 | 0.78 | TSHR (0.49) | TSHRKMT2AGAAMAPTALDH1A1 | |
| SCHEMBL26088044 | 0.77 | KMT2A (0.48) | TSHRKMT2AGAAMAPTALDH1A1 | |
| SCHEMBL12854715 | 0.77 | TSHR (0.48) | TSHRKMT2AGAAALDH1A1KDM4E | |
| SCHEMBL21408332 | 0.76 | NPSR1 (0.45) | TSHRKMT2AGAAMAPTALDH1A1 | |
| SCHEMBL21408425 | 0.76 | NPSR1 (0.48) | TSHRKMT2AGAAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115960083-A | Heterocyclic compounds, their preparation and use | 百极弘烨(南通)医药科技有限公司 | 2023-04-14 | — | — | CN | disclosed |