Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Propylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylamine SCHEMBL19809577 | 0.95 | — | — | |
| Propylamine SCHEMBL27946902 | 0.95 | — | — | |
| Propylamine SCHEMBL27914291 | 0.90 | — | — | |
| Propylamine SCHEMBL8027944 | 0.90 | — | — | |
| Propylamine SCHEMBL1791346 | 0.90 | — | — | |
| Propylamine SCHEMBL8499092 | 0.90 | — | — | |
| Propylamine SCHEMBL9181 | 0.89 | — | — | |
| Propylamine SCHEMBL448871 | 0.89 | — | — | |
| Propylamine SCHEMBL1330797 | 0.89 | — | — | |
| Propylamine SCHEMBL23706286 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115784234-B | Two-dimensional thin-layer silylene material and preparation method thereof | 大连理工大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-115784234-A | Two-dimensional thin-layer silylene material and preparation method thereof | 大连理工大学 | 2023-03-14 | — | — | CN | disclosed |