Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31634032 | 0.92 | ALDH1A1 (0.44) | ALDH1A1TDP1LMNASIRT6MAPT | |
| SCHEMBL29811305 | 0.86 | SMN1; SMN2 (0.46) | ALDH1A1TDP1LMNASIRT6MAPT | |
| SCHEMBL11962581 | 0.86 | SMN1; SMN2 (0.46) | ALDH1A1TDP1LMNASIRT6MAPT | |
| SCHEMBL31634065 | 0.83 | CHEK1 (0.45) | ALDH1A1TDP1LMNASIRT6MAPT | |
| SCHEMBL11962590 | 0.81 | ALDH1A1 (0.41) | ALDH1A1TDP1LMNASIRT6MAPT | |
| SCHEMBL7571419 | 0.80 | ALDH1A1 (0.55) | ALDH1A1TDP1LMNASIRT6MAPT | |
| SCHEMBL10848119 | 0.80 | AR (0.49) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL14993876 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TDP1LMNASIRT6MAPT | |
| SCHEMBL23093118 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TDP1LMNAMAPTHPGD | |
| SCHEMBL28826140 | 0.78 | ALDH1A1 (0.53) | ALDH1A1TDP1LMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115947728-B | Sulfonyl-containing dihydropteridinone derivatives and their use | 沈阳药科大学 | 2024-01-09 | — | — | CN | disclosed |
| CN-115947728-A | Dihydro pteridinone derivative containing sulfonyl and application thereof | 沈阳药科大学 | 2023-04-11 | — | — | CN | disclosed |