Biphenyl

Biphenyl

SCHEMBL28985247

c1ccc(-c2ccccc2)cc1.c1ccc(-c2ccccc2)cc1.c1ccc(-c2ccccc2)cc1.c1ccc(-c2ccccc2)cc1.c1ccc(-c2ccccc2)cc1.c1ccc2c(c1)[nH]c1c2ccc2sc3ccccc3c21

nearest known ligand 0.51

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 2/20 0.51
GABRD O14764 2/20 0.51
GABRA1 P14867 2/20 0.51
GABRB1 P18505 2/20 0.51
GABRG2 P18507 2/20 0.51
GABRB3 P28472 2/20 0.51
GABRA5 P31644 2/20 0.51
GABRA3 P34903 2/20 0.51
GABRA2 P47869 2/20 0.51
GABRB2 P47870 2/20 0.51
GABRA4 P48169 2/20 0.51
GABRE P78334 2/20 0.51
GABRA6 Q16445 2/20 0.51
GABRG1 Q8N1C3 2/20 0.51
GABRG3 Q99928 2/20 0.51
GABRQ Q9UN88 2/20 0.51
MEN1 O00255 3/20 0.50
MAPT P10636 3/20 0.50
KMT2A Q03164 3/20 0.50
RAB9A P51151 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29986173 0.95 GABRP (0.56) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL783085 0.95 GABRP (0.56) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL25678898 0.90 GABRP (0.44) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL15127064 0.90 GABRP (0.44) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL15126680 0.90 GABRP (0.47) GABRPGABRDGABRA1GABRB1GABRG2
Boric Acid SCHEMBL28476105 0.85 CDK4 (0.43) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL25679616 0.85 GABRP (0.49) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL25703309 0.83 CDK4 (0.46) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL18688083 0.82 CDK4 (0.40) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL18688076 0.81 MEN1 (0.50) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110845481-B 3,4-diazafluorene derivatives, method for synthesizing same, and electronic device containing 3,4-diazafluorene derivatives 苏州久显新材料有限公司 2023-04-18 CN disclosed