Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27596510 | 0.81 | NPC1 (0.58) | NPC1MAPK1ALDH1A1NOTUMHTR2C | |
| SCHEMBL28475929 | 0.79 | MAPT (0.55) | NPC1MAPK1ALDH1A1NOTUMHTR2C | |
| SCHEMBL8297949 | 0.77 | NPC1 (0.49) | NPC1MAPK1ALDH1A1NOTUMHTR2C | |
| SCHEMBL15064490 | 0.76 | NPC1 (0.51) | NPC1MAPK1ALDH1A1NOTUMHTR2C | |
| SCHEMBL30987383 | 0.76 | NPC1 (0.51) | NPC1MAPK1ALDH1A1NOTUMCYP1A2 | |
| SCHEMBL27449315 | 0.76 | NPC1 (0.47) | NPC1MAPK1ALDH1A1NOTUMHTR2C | |
| SCHEMBL3391811 | 0.76 | NPC1 (0.47) | NPC1MAPK1ALDH1A1NOTUMHTR2C | |
| SCHEMBL9394244 | 0.75 | NPC1 (0.50) | NPC1MAPK1ALDH1A1NOTUMHTR2C | |
| SCHEMBL15352629 | 0.74 | MGLL (0.37) | NPC1MAPK1ALDH1A1KDM4EMAPT | |
| SCHEMBL15352278 | 0.74 | NOTUM (0.44) | ALDH1A1NOTUMCYP1A2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115819348-B | Process for preparing N-aryl pyrazole compound | 曲靖师范学院 | 2025-03-21 | — | — | CN | disclosed |
| CN-115819348-A | Process for preparing N-arylpyrazole compound | 曲靖师范学院 | 2023-03-21 | — | — | CN | disclosed |