Tryptamine

Tryptamine

SCHEMBL28985489

Cc1ccccc1.NCCc1c[nH]c2ccccc12

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 7/20 0.81
HTR1D P28221 2/20 0.81
HTR2C P28335 2/20 0.81
CYP3A4 P08684 2/20 0.81
HTR6 P50406 2/20 0.81
MPO P05164 1/20 0.81
CYP1A2 P05177 1/20 0.81
CYP2D6 P10635 1/20 0.81
CYP2A6 P11509 1/20 0.81
NFKB1 P19838 1/20 0.81
HTR1B P28222 1/20 0.81
HTR7 P34969 1/20 0.81
CTSK P43235 1/20 0.81
CYP2A13 Q16696 1/20 0.81
TAAR1 Q96RJ0 1/20 0.81
PMP22 Q01453 1/20 0.78
HTR1A P08908 3/20 0.55
HTR2B P41595 1/20 0.55
KDM4E B2RXH2 1/20 0.55
ALDH1A1 P00352 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tryptamine SCHEMBL1172195 0.90 HTR2A (0.93) HTR2AHTR1DHTR2CCYP3A4HTR6
Tryptamine SCHEMBL8714244 0.90 HTR2A (1.00) HTR2AHTR1DHTR2CCYP3A4HTR6
Tryptamine SCHEMBL26725 0.90 HTR2A (1.00) HTR2AHTR1DHTR2CCYP3A4HTR6
Tryptamine SCHEMBL29373222 0.90 HTR2A (1.00) HTR2AHTR1DHTR2CCYP3A4HTR6
Tryptamine SCHEMBL11083140 0.88 HTR2A (0.89) HTR2AHTR1DHTR2CCYP3A4HTR6
Tryptamine SCHEMBL9472063 0.88 HTR2A (0.96) HTR2AHTR1DHTR2CCYP3A4HTR6
Tryptamine SCHEMBL274183 0.88 PMP22 (1.00) HTR2AHTR1DHTR2CCYP3A4HTR6
Tryptamine SCHEMBL22127053 0.88 HTR2A (0.96) HTR2AHTR1DHTR2CCYP3A4HTR6
Tryptamine SCHEMBL4936407 0.88 HTR2A (0.96) HTR2AHTR1DHTR2CCYP3A4HTR6
Tryptamine SCHEMBL599675 0.88 HTR2A (0.96) HTR2AHTR1DHTR2CCYP3A4HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115825030-A Method for detecting tryptamine substances on site by using colorimetric-fluorescent dual-mode detection reagent 中国科学院新疆理化技术研究所 2023-03-21 CN disclosed