Tryptamine

Tryptamine

SCHEMBL28985494

CC(C)=O.NCCc1c[nH]c2ccccc12

nearest known ligand 0.81

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.81
HTR1D P28221 3/20 0.81
HTR1B P28222 3/20 0.81
HTR7 P34969 3/20 0.81
HTR2C P28335 3/20 0.81
HTR2A P28223 3/20 0.81
HTR6 P50406 2/20 0.81
MPO P05164 1/20 0.81
CYP3A4 P08684 1/20 0.81
CYP2D6 P10635 1/20 0.81
CYP2A6 P11509 1/20 0.81
NFKB1 P19838 1/20 0.81
CTSK P43235 1/20 0.81
CYP2A13 Q16696 1/20 0.81
TAAR1 Q96RJ0 1/20 0.81
PMP22 Q01453 1/20 0.78
MEN1 O00255 3/20 0.64
KMT2A Q03164 3/20 0.64
TSHR P16473 2/20 0.64
LMNA P02545 2/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tryptamine SCHEMBL27094904 0.95 HTR1B (0.78) CYP1A2HTR1DHTR1BHTR7HTR2C
Tryptamine SCHEMBL27598897 0.95 CYP1A2 (0.78) CYP1A2HTR1DHTR1BHTR7HTR2C
Tryptamine SCHEMBL5298628 0.94 HTR1B (0.76) CYP1A2HTR1DHTR1BHTR7HTR2C
Tryptamine SCHEMBL30426532 0.92 HTR7 (0.83) CYP1A2HTR1DHTR1BHTR7HTR2C
Tryptamine SCHEMBL28751439 0.90 CYP1A2 (0.81) CYP1A2HTR1DHTR1BHTR7HTR2C
Tryptamine SCHEMBL1172195 0.90 HTR2A (0.93) CYP1A2HTR1DHTR1BHTR7HTR2C
Tryptamine SCHEMBL8714244 0.90 HTR2A (1.00) CYP1A2HTR1DHTR1BHTR7HTR2C
Tryptamine SCHEMBL29373222 0.90 HTR2A (1.00) CYP1A2HTR1DHTR1BHTR7HTR2C
Tryptamine SCHEMBL26725 0.90 HTR2A (1.00) CYP1A2HTR1DHTR1BHTR7HTR2C
Tryptamine SCHEMBL16990205 0.89 HTR2C (0.78) CYP1A2HTR1DHTR1BHTR7HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115825030-A Method for detecting tryptamine substances on site by using colorimetric-fluorescent dual-mode detection reagent 中国科学院新疆理化技术研究所 2023-03-21 CN disclosed